Good news: Complications for Type 1 are decreasing

retinaAn article published in August by the Juvenile Diabetes Research Foundation has brought great news for those of us living with the big D.

According to the study “Thirty years of data from international trials show that the rate of serious complications amongst people with type 1 diabetes is lower that was has been reported historically.”

In another article published in a diabetes journal, it was reported that the main decline has been in mortality, renal failure and neuropathy. On the other hand overt nephropathy and proliferative retinopathy do not seem to be showing such positive signs.

The other odd issue in the report is around cardio vascular disease. The researchers observed a reduction in incidence in people who have had diabetes for 20 years, but this reduction seems to disappear in those who have lived with teh condition for more than 25 years

While a lot of this reduction seem to be driven by the adoption of intensive management, there is also significant progress coming from the development and use of new technologies including insulin pumps.

Share

Advertisements

3 Responses to Good news: Complications for Type 1 are decreasing

  1. Scott S says:

    Generally, this news is positive, but not all of the findings are puzzling. The issue of cardiovascular disease, in spite of the much-trumpeted DCCT and the accompany follow-up study EDIC (which only showed a decline in CV events, not an elimination in spite of glycemic control) is that there is relatively new evidence that cardiovascular disease, at least in many cases of type 1 diabetes, may in fact, have an autoimmune basis, very similar to the etiology for their diabetes. This was reported in the March 2006 journal Diabetes (S Devaraj1, N Glaser, S Griffen, J Wang-Polagruto1, E Miguelino and I Jialal; “Increased Monocytic Activity and Biomarkers of Inflammation in Patients With Type 1 Diabetes” Diabetes, 2006 Mar; 55: 774-779. URL: http://diabetes.diabetesjournals.org/content/55/3/774.abstract) which suggests that no matter how good glycemic control may be, not all cases of cardiovascular disease can be prevented, nor can all cases be attributed to poor glycemic control. The real issue is that at present, there is NO cardiovascular disease risk model for type 1 diabetes, only a model applicable to type 2 or the general population. If the NIDDK is serious about CV disease in T1DM, they need to develop an approriate risk model applicable to this population.

  2. […] Read the rest here: Good news: Complications for Type 1 are decreasing « D and The Guy … […]

  3. […] Good news: Complications for Type 1 are decreasing « D and The Guy – A blog about Diabetes in rea… dandtheguy.com/2009/09/23/good-news-complications-for-type-1-are-decreasing – view page – cached An article published in August by the Juvenile Diabetes Research Foundation has brought great news for those of us living with the big D. — From the page […]

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: